Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 12/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668683 | 0.89 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL11903736 | 0.89 | PRSS1 (0.52) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835612 | 0.84 | PRSS1 (0.51) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835502 | 0.83 | PRSS1 (0.52) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2111643 | 0.80 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109616 | 0.80 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2111439 | 0.80 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109639 | 0.78 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2111845 | 0.78 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2112515 | 0.78 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | claimed |