Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108985 | 0.88 | MAPT (0.71) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL6814025 | 0.83 | MAPT (0.65) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL28476676 | 0.81 | MAPT (0.62) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL28759781 | 0.79 | MAPT (0.59) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL30441246 | 0.79 | MAPT (0.59) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL234314 | 0.79 | MAPT (0.59) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL989873 | 0.79 | MAPT (0.59) | MAPTGAALMNAMAPK1HTT | |
| Triphenyl Phosphate SCHEMBL30396346 | 0.79 | MAPT (0.59) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL4451361 | 0.79 | MAPT (0.69) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL19348791 | 0.78 | MAPT (0.73) | MAPTGAALMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015063516-A2 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2015-05-07 | — | — | WO | disclosed |