SCHEMBL1669128

SCHEMBL1669128

O=C(NCCO)c1cc(O)c(O)c(O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.59
ALDH1A1 P00352 4/20 0.59
POLB P06746 3/20 0.59
MAPT P10636 3/20 0.59
LMNA P02545 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
HTT P42858 2/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
NSD2 O96028 1/20 0.59
ALPL P05186 1/20 0.59
ALPI P09923 1/20 0.59
ALPG P10696 1/20 0.59
APEX1 P27695 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
CASP6 P55212 1/20 0.59
HPGD P15428 3/20 0.51
NTRK2 Q16620 1/20 0.51
TOP1 P11387 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286830 0.90 KDM4E (0.65) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL15058523 0.89 KDM4E (0.55) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL13286803 0.86 KDM4E (0.61) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL16784750 0.86 KDM4E (0.61) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL3321012 0.85 NTRK2 (0.65) KDM4EALDH1A1POLBMAPTHTT
SCHEMBL24871959 0.84 KDM4E (0.59) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL24871961 0.84 KDM4E (0.59) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL16155100 0.84 KDM4E (0.59) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL16145027 0.83 KDM4E (0.63) KDM4EALDH1A1POLBMAPTLMNA
SCHEMBL20206982 0.82 KDM4E (0.57) KDM4EALDH1A1POLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673997-B2 Work time to walk-on time ratio by adding a phenolic catalyst to polyaspartic flooring formulations COVESTRO LLC (US) 2023-06-13 US claimed
EP-4004076-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS Covestro LLC (US) 2022-06-01 EP claimed
CN-114144454-A Improved operating time to open-run time ratio by adding phenolic catalysts to polyaspartic flooring formulations 科思创有限公司 2022-03-04 CN claimed
US-20210032407-A1 WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS COVESTRO LLC 2021-02-04 US claimed
WO-2021021801-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS COVESTRO LLC (US) 2021-02-04 WO claimed
CN-103224608-A Heat-curable epoxy-amine anti-seepage sealant HENKEL KGAA 2013-07-31 CN claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO claimed
US-20100168279-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS HENKEL AG & CO. KGAA (DE) 2010-07-01 US claimed
CN-101405321-A Heat Curable Epoxy-Amine Barrier Sealants NAT STARCH CHEM INVEST (US) 2009-04-08 CN claimed
EP-2001924-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS National Starch and Chemical Investment Holding Corporation (US) 2008-12-17 EP claimed
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO claimed
US-5258427-A MIXTURE OF A LIQUID EPOXY RESIN, A METAL OXIDE AND A POLYHYDROXYARYL COMPOUND ICI AUSTRALIA OPERATIONS PROPRIETARY LTD. (AU) 1993-11-02 US claimed
EP-0458521-A2 Heat curable adhesive ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1991-11-27 EP claimed
US-20250257167-A1 EXTENDED WORK TIME POLYASPARTIC FLOOR COATING FORMULATIONS COVESTRO LLC 2025-08-14 US disclosed
EP-4526362-A1 EXTENDED WORK TIME POLYASPARTIC FLOOR COATING FORMULATIONS Covestro LLC (US) 2025-03-26 EP disclosed
CN-114144454-B Improved handling time to open walk time ratio by adding phenolic catalyst to polyaspartic floor formulation 科思创有限公司 2025-02-14 CN disclosed
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO disclosed
US-5258427-A MIXTURE OF A LIQUID EPOXY RESIN, A METAL OXIDE AND A POLYHYDROXYARYL COMPOUND ICI AUSTRALIA OPERATIONS PROPRIETARY LTD. (AU) 1993-11-02 US disclosed
EP-0458521-A2 Heat curable adhesive ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1991-11-27 EP disclosed