⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873888 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL16329660 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL1397641 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL15773944 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL16329771 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL20169646 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL725752 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL9952291 | 0.97 | HIF1A (0.32) | — | |
| SCHEMBL16329560 | 0.91 | — | — | |
| SCHEMBL3955608 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354781-A | Peptide inhibitors of interleukin-23 receptor | 西兰制药公司 | 2024-07-16 | — | — | CN | claimed |
| US-20230257354-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2023-08-17 | — | — | US | claimed |
| EP-4211116-A1 | NOVEL HETEROCYCLIC ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-07-19 | — | — | EP | claimed |
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | claimed |
| CN-116096709-A | Novel heterocyclic antibiotics | 豪夫迈·罗氏有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-118354781-A | Peptide inhibitors of interleukin-23 receptor | 西兰制药公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116940841-A | Methods for in vitro diagnosis of infection | 原始格私人有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-20230257354-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2023-08-17 | — | — | US | disclosed |
| EP-4211116-A1 | NOVEL HETEROCYCLIC ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-07-19 | — | — | EP | disclosed |
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | disclosed |
| CN-116096709-A | Novel heterocyclic antibiotics | 豪夫迈·罗氏有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20220106361-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2022-04-07 | — | — | US | disclosed |
| US-9416276-B2 | Method for producing contrast agent | CANON KABUSHIKI KAISHA (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150126749-A1 | METHOD FOR PRODUCING CONTRAST AGENT | CANON KABUSHIKI KAISHA (JP) | 2015-05-07 | — | — | US | disclosed |