SCHEMBL16693185

SCHEMBL16693185

CC/N=C1/CN2CCC1CC2

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 5/20 0.47
CHRM1 P11229 18/20 0.45
CHRM2 P08172 15/20 0.45
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16684570 0.76 CHRM1 (0.47) CHRM3CHRM1CHRM2CHRNB2CHRNA4
SCHEMBL1640874 0.76 CHRM1 (0.47) CHRM3CHRM1CHRM2CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL9041966 0.73 CHRM3 (0.78) CHRM3CHRM1CHRM2
SCHEMBL7811397 0.71 CHRM1 (0.42) CHRM3CHRM1CHRM2CHRNB2CHRNA4
SCHEMBL231365 0.71 CHRM1 (0.42) CHRM3CHRM1CHRM2CHRNB2CHRNA4
SCHEMBL16684596 0.71 CHRM1 (0.47) CHRM3CHRM1CHRM2CHRNB2CHRNA4
SCHEMBL9040900 0.71 CHRM1 (0.79) CHRM3CHRM1CHRM2
SCHEMBL9040889 0.71 CHRM1 (0.79) CHRM3CHRM1CHRM2
Hydrochloric Acid SCHEMBL9042360 0.71 CHRM1 (0.79) CHRM3CHRM1CHRM2
SCHEMBL16693156 0.71 CHRM1 (0.35) CHRM3CHRM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015066371-A1 SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS FORUM PHARMACEUTICALS, INC. (US) 2015-05-07 WO disclosed