Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16696050 | 0.94 | CYP3A4 (0.50) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696154 | 0.90 | CYP3A4 (0.49) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696090 | 0.89 | CYP3A4 (0.45) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696088 | 0.88 | CYP3A4 (0.59) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696160 | 0.87 | CYP3A4 (0.49) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696076 | 0.85 | CYP3A4 (0.50) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL16696037 | 0.85 | CYP3A4 (0.42) | CYP3A4TNKSOPRL1OPRM1 | |
| SCHEMBL16696109 | 0.83 | OPRL1 (0.44) | CYP3A4OPRL1OPRM1CYP2D6 | |
| SCHEMBL9978113 | 0.83 | CYP3A4 (0.64) | CYP3A4TNKSOPRL1OPRM1CYP2D6 | |
| SCHEMBL9977960 | 0.83 | CYP3A4 (0.66) | CYP3A4TNKSOPRL1OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |