Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16696068 | 0.90 | NPSR1 (0.43) | OPRM1NPSR1ALDH1A1POLBTSHR | |
| SCHEMBL16696110 | 0.90 | OPRL1 (0.44) | OPRM1CTSSDRD2SLC6A4CYP3A4 | |
| SCHEMBL16696072 | 0.90 | CYP3A4 (0.36) | NPSR1ALDH1A1POLBTSHRCRHBP | |
| SCHEMBL16696076 | 0.87 | CYP3A4 (0.50) | OPRM1DRD2SLC6A4CYP3A4MAT2A | |
| SCHEMBL9978103 | 0.85 | CYP3A4 (0.36) | OPRM1NPSR1TSHRCRHBPCRHR2 | |
| SCHEMBL16696107 | 0.82 | CYP3A4 (0.45) | OPRM1DRD2SLC6A4CYP3A4OPRL1 | |
| SCHEMBL9978060 | 0.81 | CYP3A4 (0.42) | OPRM1CYP3A4OPRL1 | |
| SCHEMBL16696154 | 0.81 | CYP3A4 (0.49) | OPRM1CTSSDRD2SLC6A4CYP3A4 | |
| SCHEMBL9977956 | 0.81 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL16696092 | 0.80 | OPRL1 (0.48) | OPRM1NPSR1ALDH1A1TSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |