Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685871 | 0.89 | KMT2A (0.68) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16685836 | 0.88 | KMT2A (0.64) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16686277 | 0.88 | KMT2A (0.67) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL15525610 | 0.88 | KMT2A (0.64) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16685783 | 0.88 | KMT2A (0.64) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16686240 | 0.88 | KMT2A (0.64) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16685861 | 0.87 | KMT2A (0.63) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL16685807 | 0.85 | KMT2A (0.61) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL29108825 | 0.85 | KMT2A (0.64) | KMT2AKAT8ALDH1A1HPGDNPSR1 | |
| SCHEMBL29108826 | 0.84 | KMT2A (0.62) | KMT2AKAT8ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065716-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-05-07 | — | — | WO | disclosed |