Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670331 | 0.93 | SSTR5 (0.49) | SSTR5KCNH2 | |
| SCHEMBL16670334 | 0.86 | SSTR5 (0.51) | SSTR5KCNH2 | |
| SCHEMBL16670601 | 0.81 | SSTR5 (0.39) | SSTR5ALDH1A1KCNH2KDM4EMAPT | |
| SCHEMBL16670082 | 0.79 | SSTR5 (0.38) | SSTR5KCNH2MAPT | |
| SCHEMBL16670069 | 0.78 | MEN1 (0.40) | SSTR5ALDH1A1 | |
| SCHEMBL16683346 | 0.78 | SSTR5 (0.44) | SSTR5ALDH1A1KCNH2 | |
| SCHEMBL16670319 | 0.78 | KDM4E (0.36) | SSTR5KDM4EMAPT | |
| SCHEMBL16669669 | 0.77 | SSTR5 (0.50) | SSTR5ALDH1A1KCNH2KDM4E | |
| SCHEMBL16670843 | 0.77 | SSTR5 (0.50) | SSTR5KCNH2 | |
| SCHEMBL16670554 | 0.76 | SSTR5 (0.51) | SSTR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015064083-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-07 | — | — | WO | disclosed |