Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 19/20 | 0.74 |
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.74 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706498 | 0.85 | LPAR1 (1.00) | LPAR1LPAR3HRH1 | |
| SCHEMBL16697513 | 0.80 | LPAR1 (0.75) | LPAR1LPAR3HRH1MLYCD | |
| SCHEMBL16699589 | 0.80 | LPAR1 (0.56) | LPAR1LPAR3HRH1 | |
| SCHEMBL16706499 | 0.78 | LPAR1 (1.00) | LPAR1LPAR3HRH1 | |
| SCHEMBL3678803 | 0.76 | LPAR1 (0.53) | LPAR1LPAR3MLYCD | |
| SCHEMBL2636016 | 0.74 | LPAR1 (0.54) | LPAR1LPAR3MLYCD | |
| SCHEMBL23235506 | 0.74 | LPAR1 (0.53) | LPAR1LPAR3HRH1MLYCD | |
| SCHEMBL23235418 | 0.74 | LPAR1 (0.53) | LPAR1LPAR3HRH1MLYCD | |
| SCHEMBL16700049 | 0.73 | LPAR1 (1.00) | LPAR1LPAR3HRH1 | |
| SCHEMBL16700053 | 0.73 | LPAR1 (1.00) | LPAR1LPAR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321738-B2 | N-alkyltriazole compounds as LPAR antagonists | HOFFMAN-LA ROCHE INC. (US) | 2016-04-26 | — | — | US | claimed |
| US-20150133511-A1 | N-ALKYLTRIAZOLE COMPOUNDS AS LPAR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-05-14 | — | — | US | claimed |
| US-9321738-B2 | N-alkyltriazole compounds as LPAR antagonists | HOFFMAN-LA ROCHE INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20150133511-A1 | N-ALKYLTRIAZOLE COMPOUNDS AS LPAR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133511-A1 | N-ALKYLTRIAZOLE COMPOUNDS AS LPAR ANTAGONISTS | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885LPAR3 3/4885HRH1 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.