SCHEMBL16701334

SCHEMBL16701334

NC[C@H]1CN(c2ccc(F)c(F)c2)C(=O)O1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BPTF Q12830 1/20 0.57
F10 P00742 2/20 0.55
CALML3 P27482 7/20 0.53
MAOB P27338 4/20 0.47
MAOA P21397 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47
GRM2 Q14416 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701336 1.00 BPTF (0.57) BPTFF10CALML3MAOBMAOA
SCHEMBL12157633 0.90 F10 (0.57) BPTFF10CALML3MAOBMAOA
SCHEMBL592027 0.89 F10 (0.53) F10CALML3MAOBMAOALMNA
SCHEMBL592028 0.89 F10 (0.53) F10CALML3MAOBMAOALMNA
SCHEMBL1394138 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA
SCHEMBL1036374 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA
SCHEMBL2107338 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA
SCHEMBL5917588 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA
SCHEMBL4574017 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA
SCHEMBL4574013 0.88 F10 (0.52) BPTFF10CALML3MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3065740-B1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LTD (IN) 2018-08-22 EP claimed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US claimed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US claimed
EP-3065740-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND Lee Pharma Ltd. (IN) 2016-09-14 EP claimed
WO-2015068171-A1 NOVEL OXAZOLIDINONE COMPOUNDS LEE PHARMA LIMITED (IN) 2015-05-14 WO claimed
WO-2015068173-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LIMITED (IN) 2015-05-14 WO claimed
EP-3065740-B1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LTD (IN) 2018-08-22 EP disclosed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US disclosed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US disclosed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US disclosed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US disclosed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US disclosed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US disclosed
EP-3065740-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND Lee Pharma Ltd. (IN) 2016-09-14 EP disclosed
WO-2015068171-A1 NOVEL OXAZOLIDINONE COMPOUNDS LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed
WO-2015068173-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed
WO-2015068173-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed
WO-2015068171-A1 NOVEL OXAZOLIDINONE COMPOUNDS LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound OXA1L, ODC1, AZI2 BPTF 3050/4885F10 707/4885CALML3 2210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.