Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | RAD52 | P43351 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760646 | 0.94 | HRH3 (0.70) | HRH3TSHRACHERAD52 | |
| SCHEMBL3571025 | 0.87 | HRH3 (0.79) | HRH3TSHRACHERAD52 | |
| Jnj-5207852 SCHEMBL3577334 | 0.85 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL3580340 | 0.85 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL3572587 | 0.85 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL16702209 | 0.84 | HRH3 (0.68) | HRH3TSHRACHERAD52 | |
| SCHEMBL10661541 | 0.84 | HRH3 (0.74) | HRH3TSHRACHERAD52 | |
| SCHEMBL3580727 | 0.83 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL30777699 | 0.83 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| Hydrochloric Acid SCHEMBL16702258 | 0.83 | HRH3 (0.67) | HRH3TSHRACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |
| CN-100384850-C | Galantamine derivative and its prepn process and use | UNIV ZHEJIANG (CN) | 2008-04-30 | — | — | CN | disclosed |
| CN-1847246-A | Galantamine derivative and its prepn process and use | UNIV ZHEJIANG (CN) | 2006-10-18 | — | — | CN | disclosed |