Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL611794 | 0.81 | — | — | |
| SCHEMBL112351 | 0.81 | — | — | |
| Phosphoric Acid SCHEMBL6858708 | 0.72 | HPGD (0.31) | — | |
| SCHEMBL32684053 | 0.64 | — | — | |
| SCHEMBL19306615 | 0.63 | MAPT (0.47) | MAPTSMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL2875683 | 0.62 | — | — | |
| SCHEMBL16200056 | 0.62 | — | — | |
| SCHEMBL2724008 | 0.60 | LRRK2 (0.46) | DYRK1ASMN1; SMN2PDE4DTSHR | |
| SCHEMBL3263794 | 0.60 | LRRK2 (0.45) | DYRK1A | |
| SCHEMBL31124676 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066080-B1 | NOVEL COMPOUNDS FOR COMBATING ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3066079-B1 | NOVEL COMPOUNDS FOR COMBATING ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3066080-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-3066079-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067646-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067647-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |