SCHEMBL16704392

SCHEMBL16704392

CN(c1ccccc1)c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c(c3)C(C)(C)c3cc(N(c5ccccc5)c5ccccc5)ccc3-4)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.48
CHKA P35790 4/20 0.37
NR3C2 P08235 1/20 0.36
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TLR9 Q9NR96 2/20 0.33
CRHBP P24387 1/20 0.33
ATM Q13315 1/20 0.33
CRHR2 Q13324 1/20 0.33
GSK3B P49841 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14465505 0.97 PDK2 (0.49) PDK2CHKANR3C2ALDH1A1L3MBTL1
SCHEMBL16704394 0.96 PDK2 (0.51) PDK2CHKANR3C2ALDH1A1L3MBTL1
SCHEMBL16837423 0.94 PDK2 (0.50) PDK2CHKANR3C2ALDH1A1L3MBTL1
SCHEMBL279630 0.94 PDK2 (0.54) PDK2CHKANR3C2ALDH1A1L3MBTL1
SCHEMBL14340295 0.94 PDK2 (0.39) PDK2ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL14340188 0.94 PDK2 (0.39) PDK2ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL14340168 0.94 PDK2 (0.39) PDK2ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL13020810 0.94 PDK2 (0.39) PDK2ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL14465457 0.93 PDK2 (0.54) PDK2CHKANR3C2ALDH1A1L3MBTL1
SCHEMBL15496091 0.92 PDK2 (0.38) PDK2ALDH1A1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028980-B2 Organic electroluminescent element, composition for organic electroluminescent element, and organic electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-12 US disclosed