Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NT5E | P21589 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.68 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.68 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.68 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.67 |
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | F3 | P13726 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | GLI1 | P08151 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293178 | 1.00 | GPBAR1 (0.69) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL3507541 | 1.00 | GPBAR1 (0.69) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL16704671 | 0.93 | EGLN2 (0.65) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13304146 | 0.92 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13293261 | 0.92 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL16704971 | 0.91 | EGLN2 (0.67) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL15450694 | 0.91 | EGLN2 (0.67) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13293163 | 0.89 | EGLN2 (0.83) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL14086933 | 0.89 | EGLN2 (0.83) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL14554423 | 0.89 | GPBAR1 (0.72) | GPBAR1LMNANT5ESMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029414-B2 | Triterpenoid compounds and methods of use thereof | BIOTECHNOLOGY RESEARCH CORPORATION (HK) | 2015-05-12 | — | — | US | disclosed |