Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353279 | 0.83 | ADORA2A (0.76) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1355354 | 0.83 | ADORA2A (0.76) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1353128 | 0.82 | ADORA2A (0.56) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1355553 | 0.81 | ADORA2A (0.73) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL12134407 | 0.79 | ADORA2A (0.51) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1352825 | 0.77 | ADORA2A (1.00) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1356263 | 0.77 | ADORA2A (1.00) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL13284827 | 0.77 | ADORA2A (0.47) | ADORA2AMKNK1MKNK2CYP3A4EIF4E | |
| SCHEMBL1356341 | 0.70 | ADORA2A (1.00) | ADORA2AMKNK1MKNK2EIF4E | |
| SCHEMBL1356309 | 0.70 | ADORA2A (0.80) | ADORA2AMKNK1MKNK2EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029393-B2 | Adenosine receptor ligands and uses thereof | KALDI PHARMA, SAS (FR) | 2015-05-12 | — | — | US | disclosed |