SCHEMBL16705248

SCHEMBL16705248

CCCn1c(C[C@H](C)OC)nc2c(N)nc3cc(OC4CCN(C(N)=O)CC4)ccc3c21

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 17/20 0.44
TLR8 Q9NR97 11/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247588 0.88 TLR7 (0.52) TLR7TLR8
SCHEMBL4240274 0.82 TLR7 (0.50) TLR7TLR8
SCHEMBL4246801 0.81 TLR7 (0.52) TLR7TLR8
SCHEMBL5617751 0.81 TLR7 (0.50) TLR7TLR8
SCHEMBL4240314 0.80 TLR7 (0.47) TLR7TLR8
SCHEMBL4243570 0.80 TLR7 (0.47) TLR7TLR8
SCHEMBL5617649 0.80 TLR7 (0.47) TLR7TLR8
SCHEMBL4241253 0.78 TLR7 (0.49) TLR7TLR8
SCHEMBL5618316 0.77 TLR7 (0.48) TLR7TLR8
SCHEMBL4240706 0.75 TLR8 (0.44) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673087-B1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2015-05-13 EP disclosed