SCHEMBL16705283

SCHEMBL16705283

CC(C)(CBr)C(=O)Nc1ccc(C#N)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 16/20 0.56
IDO1 P14902 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850948 0.88 AR (0.64) AR
SCHEMBL2284951 0.88 AR (0.64) AR
SCHEMBL18171617 0.88 AR (0.64) AR
SCHEMBL17643980 0.88 AR (0.64) AR
SCHEMBL12050119 0.86 AR (0.58) ARIDO1
SCHEMBL31053809 0.86 AR (0.58) ARIDO1
SCHEMBL2481947 0.83 AR (0.61) ARIDO1
SCHEMBL16705284 0.82 AR (0.60) AR
SCHEMBL19964399 0.82 AR (0.65) AR
SCHEMBL20752878 0.82 AR (0.65) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2871177-A1 Solid form of (R) or (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide GTX, Inc. (US) 2015-05-13 EP disclosed