⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113558 | 0.73 | — | — | |
| SCHEMBL1668792 | 0.72 | — | — | |
| SCHEMBL9147430 | 0.72 | — | — | |
| SCHEMBL26695487 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28656049 | 0.69 | — | — | |
| SCHEMBL29064633 | 0.69 | — | — | |
| SCHEMBL23692831 | 0.69 | — | — | |
| SCHEMBL3073644 | 0.69 | — | — | |
| SCHEMBL23691212 | 0.67 | — | — | |
| SCHEMBL26832 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649061-B1 | PYRIDINE AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS | Rottapharm Biotech Srl (IT) | 2015-05-13 | — | — | EP | disclosed |