Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706193 | 1.00 | TSHR (0.53) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL9962957 | 0.98 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL139326 | 0.98 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10030114 | 0.98 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL15293381 | 0.93 | TSHR (0.57) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10301166 | 0.93 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31187428 | 0.93 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31187421 | 0.93 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31187424 | 0.93 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL19822567 | 0.93 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266985-B2 | Silicone compound and a use thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-02-23 | — | — | US | disclosed |
| US-20150133619-A1 | SILICONE COMPOUND AND A USE THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133619-A1 | SILICONE COMPOUND AND A USE THEREOF | STIM1, SMCHD1, SHC1 | TSHR 3917/4885MEN1 23/4885KMT2A 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.