Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.53 |
| ▸ | ACE | P12821 | 12/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188440 | 0.88 | F2 (0.45) | F2ACEPRSS1FKBP1A | |
| SCHEMBL20188311 | 0.88 | F2 (0.45) | F2ACEPRSS1FKBP1A | |
| SCHEMBL24448344 | 0.88 | DPP4 (0.46) | F2ACEPRSS1 | |
| SCHEMBL28389317 | 0.87 | DPP4 (0.46) | F2PRSS1 | |
| SCHEMBL18094995 | 0.87 | DPP4 (0.46) | F2PRSS1 | |
| SCHEMBL20859024 | 0.86 | F2 (0.51) | F2ACEACE2PRSS1 | |
| SCHEMBL20859032 | 0.86 | F2 (0.46) | F2ACEPRSS1 | |
| SCHEMBL23863889 | 0.86 | F2 (0.46) | F2ACEPRSS1 | |
| SCHEMBL20188058 | 0.85 | DPP4 (0.43) | F2PRSS1FKBP1A | |
| SCHEMBL20188054 | 0.85 | DPP4 (0.43) | F2PRSS1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015067923-A1 | NMDA ANTAGONIST PRODRUGS | ASTRAZENECA AB (SE) | 2015-05-14 | — | — | WO | disclosed |