Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670701 | 1.00 | CHEK1 (0.31) | CHEK1NTRK1PIM1CDK2CSNK2A1 | |
| SCHEMBL1670706 | 0.80 | — | — | |
| SCHEMBL1670827 | 0.72 | — | — | |
| SCHEMBL1670825 | 0.72 | — | — | |
| SCHEMBL1670939 | 0.69 | BRD4 (0.32) | — | |
| SCHEMBL1670941 | 0.69 | BRD4 (0.32) | — | |
| SCHEMBL1671705 | 0.68 | KDM1A (0.30) | — | |
| SCHEMBL1671703 | 0.68 | KDM1A (0.30) | — | |
| SCHEMBL1671330 | 0.67 | — | — | |
| SCHEMBL1670539 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |