Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.53 |
| ▸ | AHCY | P23526 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936606 | 1.00 | SLC29A1 (0.53) | SLC29A1AHCYADORA2AADORA3ADORA1 | |
| SCHEMBL12936602 | 1.00 | SLC29A1 (0.53) | SLC29A1AHCYADORA2AADORA3ADORA1 | |
| SCHEMBL16707276 | 1.00 | SLC29A1 (0.53) | SLC29A1AHCYADORA2AADORA3ADORA1 | |
| SCHEMBL16707281 | 0.87 | SLC29A1 (0.68) | SLC29A1ADORA2AADORA3ADORA1TSHR | |
| SCHEMBL12803548 | 0.87 | SLC29A1 (0.68) | SLC29A1ADORA2AADORA3ADORA1TSHR | |
| SCHEMBL12936603 | 0.87 | SLC29A1 (0.68) | SLC29A1ADORA2AADORA3ADORA1TSHR | |
| SCHEMBL16707283 | 0.87 | SLC29A1 (0.68) | SLC29A1ADORA2AADORA3ADORA1TSHR | |
| SCHEMBL12964492 | 0.87 | SLC29A1 (0.68) | SLC29A1ADORA2AADORA3ADORA1TSHR | |
| SCHEMBL12936677 | 0.79 | SLC29A1 (0.56) | SLC29A1ADORA2AADORA1 | |
| SCHEMBL12803595 | 0.79 | SLC29A1 (0.56) | SLC29A1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512426-B2 | Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications | SIRNA THERAPEUTICS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150132761-A1 | METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS | BANK OF AMERICA, N.A. | 2015-05-14 | — | — | US | disclosed |