Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12803763 | 1.00 | TYMP (0.43) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL12964677 | 1.00 | TYMP (0.43) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL12803769 | 1.00 | TYMP (0.43) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL17861001 | 0.95 | TYMP (0.44) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL30866953 | 0.95 | TYMP (0.44) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL23138150 | 0.94 | TYMP (0.45) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL668619 | 0.94 | TYMP (0.45) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL7066599 | 0.94 | TYMP (0.43) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL31329389 | 0.93 | KDM4E (0.46) | TYMPKDM4ETAS1R3TAS1R1NT5E | |
| SCHEMBL25233120 | 0.93 | TYMP (0.42) | TYMPKDM4ETAS1R3TAS1R1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512426-B2 | Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications | SIRNA THERAPEUTICS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150132761-A1 | METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS | BANK OF AMERICA, N.A. | 2015-05-14 | — | — | US | disclosed |