Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167102 | 1.00 | ABCG2 (0.56) | ABCG2TDP1KRASGLAIAPP | |
| SCHEMBL18135275 | 0.89 | IAPP (0.54) | ABCG2TDP1KRASGLAIAPP | |
| SCHEMBL1405023 | 0.87 | SMN1; SMN2 (0.63) | TDP1HPGDLMNASMN1; SMN2ALOX12 | |
| SCHEMBL1405022 | 0.87 | SMN1; SMN2 (0.63) | TDP1HPGDLMNASMN1; SMN2ALOX12 | |
| SCHEMBL29090928 | 0.84 | KDM4E (0.57) | ABCG2KRASHPGDLMNASMN1; SMN2 | |
| SCHEMBL3574506 | 0.83 | ABCG2 (0.59) | ABCG2TDP1KRASHPGDLMNA | |
| SCHEMBL3574508 | 0.83 | ABCG2 (0.59) | ABCG2TDP1KRASHPGDLMNA | |
| SCHEMBL1226433 | 0.81 | ABCG2 (0.58) | ABCG2KRASHPGDLMNASMN1; SMN2 | |
| SCHEMBL1226435 | 0.81 | ABCG2 (0.58) | ABCG2KRASHPGDLMNASMN1; SMN2 | |
| SCHEMBL5750500 | 0.79 | ABCG2 (0.56) | ABCG2KRASHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9131693-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2611297-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8754115-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |
| WO-2002012172-A1 | UNSATURATED OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2002-02-14 | — | — | WO | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |
| US-6303818-B1 | Unsaturated oxime ethers and their use as fungicides | DOW AGROSCIENCES LLC | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | ABCG2 883/4885TDP1 891/4885KRAS 2752/4885 |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | ABCG2 883/4885TDP1 891/4885KRAS 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.