Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708538 | 1.00 | NPSR1 (0.31) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL16710444 | 0.96 | NPSR1 (0.32) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL16710859 | 0.96 | NPSR1 (0.32) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL19101733 | 0.93 | NPSR1 (0.30) | NPSR1EGLN2 | |
| SCHEMBL16708541 | 0.93 | NPSR1 (0.30) | NPSR1EGLN2 | |
| SCHEMBL23844102 | 0.91 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL27436084 | 0.91 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL19778894 | 0.90 | CYP3A4 (0.30) | — | |
| SCHEMBL26288320 | 0.89 | EGLN2 (0.33) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL19101835 | 0.86 | TMPRSS2 (0.35) | NPSR1EGLN2TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069939-A1 | PYRROLO [1,2,F] [1,2,4] TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2015-05-14 | — | — | WO | disclosed |