Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.40 |
| ▸ | SYK | P43405 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712265 | 1.00 | BTK (0.41) | BTKAURKASYK | |
| SCHEMBL1068183 | 0.83 | BTK (0.58) | BTKAURKASYK | |
| SCHEMBL16712264 | 0.79 | AURKA (0.41) | BTKAURKASYK | |
| SCHEMBL27737926 | 0.76 | BTK (0.57) | BTK | |
| SCHEMBL27737943 | 0.75 | BTK (0.54) | BTK | |
| SCHEMBL27716943 | 0.75 | BTK (0.52) | BTK | |
| SCHEMBL27716852 | 0.74 | BTK (0.53) | BTK | |
| SCHEMBL27716825 | 0.74 | BTK (0.51) | BTK | |
| SCHEMBL27737908 | 0.74 | BTK (0.55) | BTK | |
| SCHEMBL27737929 | 0.74 | BTK (0.53) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863766-B1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | GILEAD CONNECTICUT INC (US) | 2015-05-20 | — | — | EP | disclosed |