Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712338 | 0.89 | PPARG (0.40) | PPARGMEN1KMT2APOLBKLK7 | |
| SCHEMBL16712301 | 0.89 | PPARG (0.40) | PPARGMEN1KMT2APOLBKLK7 | |
| SCHEMBL16712329 | 0.86 | NPSR1 (0.38) | PPARGKMT2APOLBNPSR1HDAC6 | |
| SCHEMBL1077207 | 0.81 | EGFR (0.41) | MEN1KMT2APOLBKLK7THRB | |
| SCHEMBL30385663 | 0.81 | EGFR (0.41) | MEN1KMT2APOLBKLK7THRB | |
| SCHEMBL1077205 | 0.81 | EGFR (0.41) | MEN1KMT2APOLBKLK7THRB | |
| SCHEMBL16712327 | 0.81 | PPARG (0.41) | PPARGKMT2APOLBNPSR1HPGD | |
| SCHEMBL1075588 | 0.78 | GFER (0.47) | PPARGMEN1KMT2APOLBKLK7 | |
| SCHEMBL2313630 | 0.78 | GFER (0.47) | PPARGMEN1KMT2APOLBKLK7 | |
| SCHEMBL1075587 | 0.78 | GFER (0.47) | PPARGMEN1KMT2APOLBKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276732-B1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KAROBIO AB (SE) | 2015-05-20 | — | — | EP | claimed |