Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502773 | 0.96 | HRH3 (0.70) | HRH3KCNH2ADRA1A | |
| SCHEMBL4485207 | 0.92 | HRH3 (0.69) | HRH3KCNH2ADRA1A | |
| Hydrochloric Acid SCHEMBL4469898 | 0.92 | HRH3 (0.68) | HRH3KCNH2ADRA1A | |
| SCHEMBL4465686 | 0.88 | HRH3 (0.67) | HRH3KCNH2ADRA1A | |
| SCHEMBL2662165 | 0.86 | HRH3 (0.79) | HRH3KCNH2ADRA1A | |
| SCHEMBL502317 | 0.84 | HRH3 (0.79) | HRH3KCNH2ADRA1A | |
| SCHEMBL4468499 | 0.84 | HRH3 (0.77) | HRH3KCNH2ADRA1A | |
| Hydrochloric Acid SCHEMBL4471965 | 0.83 | HRH3 (0.78) | HRH3KCNH2ADRA1A | |
| SCHEMBL4468136 | 0.83 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL4458996 | 0.81 | HRH3 (0.75) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2698157-B1 | Method of treatment using fatty acid synthesis inhibitors | MERCK SHARP & DOHME (US) | 2015-05-20 | — | — | EP | disclosed |