Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233495 | 0.88 | MAP3K5 (0.60) | MAP3K5 | |
| SCHEMBL231009 | 0.88 | MAP3K5 (0.60) | MAP3K5 | |
| SCHEMBL231010 | 0.88 | MAP3K5 (0.60) | MAP3K5 | |
| SCHEMBL232980 | 0.77 | MAP3K5 (0.74) | MAP3K5 | |
| SCHEMBL231900 | 0.73 | MAP3K5 (0.71) | MAP3K5 | |
| SCHEMBL29473528 | 0.72 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL945002 | 0.72 | MAP3K5 (0.74) | MAP3K5 | |
| SCHEMBL945832 | 0.72 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL231879 | 0.71 | MAP3K5 (0.68) | MAP3K5 | |
| SCHEMBL231878 | 0.71 | MAP3K5 (0.68) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588475-B1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2015-05-20 | — | — | EP | claimed |