Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558708 | 0.81 | KHK (1.00) | KHKKCNH2 | |
| SCHEMBL12239964 | 0.78 | KHK (1.00) | KHK | |
| SCHEMBL16712502 | 0.78 | KHK (1.00) | KHKKCNH2 | |
| Hydrochloric Acid SCHEMBL2548617 | 0.77 | KHK (0.98) | KHK | |
| SCHEMBL2564804 | 0.77 | KHK (0.69) | KHK | |
| SCHEMBL17439549 | 0.76 | KHK (0.61) | KHKKCNH2 | |
| SCHEMBL2559426 | 0.75 | KHK (1.00) | KHKKCNH2 | |
| SCHEMBL12239990 | 0.75 | KHK (1.00) | KHKKCNH2 | |
| SCHEMBL12239970 | 0.74 | KHK (1.00) | KHK | |
| Hydrochloric Acid SCHEMBL2548683 | 0.74 | KHK (0.98) | KHKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560962-B1 | INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-20 | — | — | EP | disclosed |