SCHEMBL16714848

SCHEMBL16714848

CO[Si](CC(C)N1CCCCC1)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 2/20 0.30
ALDH1A1 P00352 2/20 0.30
KMT2A Q03164 2/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714767 0.82 CYP3A4 (0.34) CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL16714874 0.82 CYP3A4 (0.31) CYP3A4CYP2D6CYP2C19
SCHEMBL16714849 0.80 KMT2A (0.43) CYP2D6CYP2C19MEN1ALDH1A1KMT2A
SCHEMBL16714727 0.80 CYP3A4 (0.30) CYP3A4CYP2D6CYP2C19
SCHEMBL27565285 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C19MEN1ALDH1A1
SCHEMBL22724865 0.71 KMT2A (0.41) CYP3A4CYP2D6CYP2C19ALDH1A1KMT2A
SCHEMBL17237661 0.71 KMT2A (0.41) CYP3A4CYP2D6CYP2C19ALDH1A1KMT2A
SCHEMBL16714839 0.71
SCHEMBL16714748 0.71
SCHEMBL23254090 0.70 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C19MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104650357-B Composition and preparation method thereof comprising nitrogenous organic oxysilane compound 信越化学工业株式会社 2019-08-02 CN disclosed
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
CN-104650357-A Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO 2015-05-27 CN disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed