Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16529577 | 0.80 | DDR1 (0.51) | DDR1TMPRSS4 | |
| SCHEMBL16529578 | 0.78 | DDR1 (0.43) | DDR1TMPRSS4 | |
| SCHEMBL16715087 | 0.73 | DDR1 (0.38) | DDR1TMPRSS4 | |
| SCHEMBL16529985 | 0.67 | DDR1 (0.69) | DDR1TMPRSS4 | |
| SCHEMBL16676293 | 0.65 | DDR1 (0.38) | DDR1 | |
| SCHEMBL16528496 | 0.65 | DDR1 (0.59) | DDR1 | |
| SCHEMBL31543932 | 0.63 | KMT2A (0.41) | — | |
| SCHEMBL16529280 | 0.63 | KDM4E (0.46) | — | |
| SCHEMBL15358088 | 0.62 | SLC6A2 (0.54) | DDR1 | |
| SCHEMBL16529229 | 0.62 | KDM4E (0.50) | RXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141400-A1 | QUINAZOLINEDIONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141400-A1 | QUINAZOLINEDIONE DERIVATIVE | PPARD, SLC5A2, PPARG | DDR1 2764/4885TMPRSS4 1482/4885HCRTR1 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.