Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715321 | 0.88 | CNR2 (0.41) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| SCHEMBL16715287 | 0.83 | HPGD (0.40) | HPGDALDH1A1CNR2SMN1; SMN2CNR1 | |
| SCHEMBL807934 | 0.81 | HPGD (0.56) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL15226571 | 0.80 | HPGD (0.54) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| SCHEMBL16715268 | 0.80 | HPGD (0.50) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL15226913 | 0.78 | HPGD (0.53) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| SCHEMBL382428 | 0.77 | ACP3 (0.43) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| SCHEMBL167206 | 0.76 | CNR2 (0.42) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 | |
| SCHEMBL10129808 | 0.75 | AVPR2 (0.49) | HPGDALDH1A1CNR2SMN1; SMN2CNR1 | |
| SCHEMBL380984 | 0.75 | CNR2 (0.41) | HPGDALDH1A1CNR2SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616448-B1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER IP GMBH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-9034855-B2 | Substituted phenylacetate and phenylpropane amides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |