Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 4/20 | 0.32 |
| ▸ | CCND1 | P24385 | 4/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188217 | 0.83 | HTR2C (0.61) | HTR2AHTR2CCDK4CCND1HTR1D | |
| SCHEMBL6754186 | 0.81 | HTR2A (0.50) | HTR2AHTR2CCDK4CCND1HTR1D | |
| SCHEMBL189124 | 0.80 | CDK4 (0.35) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL16719749 | 0.79 | CYP3A4 (0.45) | HTR2AHTR2C | |
| SCHEMBL694594 | 0.77 | CDK4 (0.41) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL6228700 | 0.77 | CDK4 (0.35) | CDK4CCND1 | |
| SCHEMBL6231638 | 0.76 | HTR2C (0.33) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL6229841 | 0.76 | HTR2C (0.41) | HTR2AHTR2C | |
| SCHEMBL6229331 | 0.76 | GRM2 (0.34) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL5814894 | 0.75 | CDK4 (0.44) | HTR2AHTR2CCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |