⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720241 | 0.85 | — | — | |
| SCHEMBL16720365 | 0.81 | — | — | |
| SCHEMBL686703 | 0.72 | CYP2A6 (0.40) | — | |
| SCHEMBL16720401 | 0.70 | — | — | |
| SCHEMBL18227585 | 0.70 | — | — | |
| SCHEMBL16719574 | 0.69 | — | — | |
| SCHEMBL3211956 | 0.69 | NOTUM (0.58) | — | |
| SCHEMBL2365253 | 0.68 | CDK4 (0.35) | — | |
| SCHEMBL6986127 | 0.68 | — | — | |
| SCHEMBL18230328 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |