Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695804 | 0.83 | CDC7 (0.39) | CDC7CDK2ROCK1 | |
| SCHEMBL694480 | 0.80 | ROCK1 (0.36) | CDC7CDK2MAPTROCK1 | |
| SCHEMBL693862 | 0.79 | CYP19A1 (0.42) | CDC7CDK2MAPT | |
| SCHEMBL16719724 | 0.77 | FGFR1 (0.40) | — | |
| SCHEMBL16719625 | 0.75 | BIRC5 (0.39) | — | |
| SCHEMBL16720493 | 0.74 | ESR1 (0.35) | — | |
| SCHEMBL16720917 | 0.74 | MAPT (0.33) | MAPT | |
| SCHEMBL16720581 | 0.74 | BIRC5 (0.36) | — | |
| SCHEMBL695288 | 0.72 | ROCK1 (0.45) | CDC7CDK2ROCK1 | |
| SCHEMBL694759 | 0.72 | RPS6KA5 (0.47) | CDC7CDK2MAPTROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |