Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671707 | 0.90 | HCRTR2 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1671562 | 0.87 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1672255 | 0.86 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1671111 | 0.86 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1671485 | 0.85 | HCRTR1 (0.54) | HCRTR2HCRTR1 | |
| SCHEMBL1671730 | 0.84 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1671462 | 0.83 | HCRTR2 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL1671970 | 0.82 | HCRTR1 (0.69) | HCRTR2HCRTR1 | |
| SCHEMBL1671091 | 0.81 | HCRTR1 (0.67) | HCRTR2HCRTR1 | |
| SCHEMBL6925046 | 0.81 | HCRTR2 (1.00) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491038-A1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011050198-A1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C] PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |