Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723321 | 0.92 | GAA (0.33) | GAATSHR | |
| SCHEMBL16723306 | 0.90 | MAPT (0.37) | GAATSHRMAPT | |
| SCHEMBL16722956 | 0.88 | HCRTR2 (0.30) | — | |
| SCHEMBL16723345 | 0.86 | GAA (0.36) | GAATSHRMAPTRECQL | |
| SCHEMBL16723237 | 0.85 | MAPT (0.40) | GAATSHRMAPT | |
| SCHEMBL16723295 | 0.85 | GAA (0.37) | GAATSHRMAPTRECQL | |
| SCHEMBL16722922 | 0.84 | TSHR (0.41) | TSHR | |
| SCHEMBL16722961 | 0.83 | — | — | |
| SCHEMBL16722960 | 0.83 | — | — | |
| SCHEMBL16722942 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074081-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |