SCHEMBL1672300

SCHEMBL1672300

CC(=Cc1cc2onc(CCc3sc4cc(C(F)(F)F)ccc4c3C(C)C)c2cc1C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.47
PPARG P37231 4/20 0.47
PPARD Q03181 4/20 0.47
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12648231 0.88 PPARD (0.47) PPARAPPARGPPARDLDHALDHB
SCHEMBL1034986 0.88 PPARD (0.47) PPARAPPARGPPARDLDHALDHB
SCHEMBL1672301 0.85 PPARG (0.47) PPARAPPARGPPARDLDHALDHB
SCHEMBL12648232 0.85 PPARG (0.46) PPARAPPARGPPARD
SCHEMBL1033782 0.85 PPARG (0.46) PPARAPPARGPPARD
SCHEMBL1672559 0.84 PPARG (0.48) PPARAPPARGPPARDLDHALDHB
SCHEMBL1673112 0.84 PPARA (0.49) PPARAPPARGPPARDLDHALDHB
SCHEMBL1034117 0.84 PPARG (0.47) PPARAPPARGPPARD
SCHEMBL1033114 0.83 PPARG (0.47) PPARAPPARGPPARDLDHALDHB
SCHEMBL1031555 0.83 PPARG (0.45) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011020001-A9 USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES CERENIS THERAPEUTICS S.A. (FR) 2011-05-26 WO disclosed
US-20110092517-A1 Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases Cerenis Therapeutics S.A. & Nippon Chemiphar Co., Ltd. 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092517-A1 Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases PPARD, PPARG, PPARA PPARA 3/4885PPARG 2/4885PPARD 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.