SCHEMBL1672306

SCHEMBL1672306

Nc1nc2c(c(=S)[nH]1)NCN2CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 6/20 0.41
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7745044 0.74 HPRT1 (0.41) HPRT1HSD17B10
Adamantane SCHEMBL10430835 0.71 HPRT1 (0.52) HPRT1
SCHEMBL5250159 0.71 HPRT1 (0.60) HPRT1
SCHEMBL10917986 0.69 HPRT1 (0.52) HPRT1HSD17B10
SCHEMBL10919938 0.68 HPRT1 (0.54) HPRT1HSD17B10
SCHEMBL453175 0.67 HPRT1 (0.31) HPRT1
SCHEMBL8529902 0.67 HPRT1 (0.58) HPRT1HSD17B10
SCHEMBL10510178 0.66 HPRT1 (0.54) HPRT1HSD17B10
Acetic Acid SCHEMBL11246096 0.65 HPRT1 (0.54) HPRT1HSD17B10
SCHEMBL10506681 0.64 HPRT1 (0.48) HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200292535-A1 METHOD FOR EVALUATION OF TARGET IN HISTOLOGICAL SAMPLE DAKO DENMARK A/S (DK) 2020-09-17 US disclosed
US-10648970-B2 Method for evaluation of target in histological sample AGILENT TECHNOLOGIES, INC. (US) 2020-05-12 US disclosed
EP-2646795-B1 METHODS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK AS (DK) 2019-02-20 EP disclosed
US-10180426-B2 Quantification of single target molecules in histological samples DAKO DENMARK A/S (DK) 2019-01-15 US disclosed
US-9970874-B2 Methods and systems for analyzing images of specimens processed by a programmable quantitative assay DAKO DENMARK A/S (DK) 2018-05-15 US disclosed
US-9958449-B2 Method for enzyme-mediated signal amplification DAKO DENMARK A/S (DK) 2018-05-01 US disclosed
EP-2699691-B1 NEW METHOD FOR ENZYME-MEDIATED SIGNAL AMPLIFICATION DAKO DENMARK AS (DK) 2017-10-18 EP disclosed
US-9671400-B2 Conjugate molecules DAKO DENMARK A/S (DK) 2017-06-06 US disclosed
CN-103597089-B method for enzyme-mediated signal amplification 丹麦达科有限公司 2017-04-12 CN disclosed
CN-103649713-B Image analysis method and system for samples processed by programmable quantitative assays 丹麦达科有限公司 2017-03-01 CN disclosed
EP-2491390-A1 IMMUNOCHEMICAL DETECTION OF SINGLE TARGET ENTITIES Dako Denmark A/S (DK) 2012-08-29 EP disclosed
US-20120163681-A1 METHODS AND SYSTEMS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK APS (DK) 2012-06-28 US disclosed
WO-2012075028-A1 METHODS AND SYSTEMS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK A/S (DK) 2012-06-07 WO disclosed
WO-2012062318-A1 QUANTIFICATION OF SINGLE TARGET MOLECULES IN HISTOLOGICAL SAMPLES DAKO DENMARK A/S (DK) 2012-05-18 WO disclosed
CN-102325895-A Conjugate molecules DAKO DENMARK AS 2012-01-18 CN disclosed
WO-2011047680-A1 IMMUNOCHEMICAL DETECTION OF SINGLE TARGET ENTITIES DAKO DENMARK A/S (DK) 2011-04-28 WO disclosed
US-20100240085-A1 CONJUGATE MOLECULES DAKO DENMARK APS (DK) 2010-09-23 US disclosed
US-20100240047-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK APS (DK) 2010-09-23 US disclosed
WO-2010094284-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed
WO-2010094283-A1 CONJUGATE MOLECULES DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed