Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901212 | 0.84 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL6900585 | 0.73 | HCRTR2 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL6901250 | 0.72 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL1671929 | 0.72 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL17256244 | 0.71 | MYC (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL29713617 | 0.70 | HCRTR1 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL6923867 | 0.70 | HCRTR1 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL1672440 | 0.70 | TSHR (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL3335455 | 0.69 | CHRNA4 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL28339833 | 0.69 | KDM4E (0.40) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491034-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011050200-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |