Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707875 | 1.00 | KMT2A (0.51) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16724866 | 1.00 | KMT2A (0.51) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16710529 | 0.89 | MEN1 (0.52) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16710525 | 0.89 | MEN1 (0.52) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16710526 | 0.89 | MEN1 (0.52) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16707867 | 0.88 | KMT2A (0.54) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL16707874 | 0.88 | KMT2A (0.54) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL15536611 | 0.85 | MEN1 (0.57) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL24180467 | 0.81 | KMT2A (0.57) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL25761315 | 0.81 | KMT2A (0.57) | KMT2AMEN1TSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150136700-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2015-05-21 | — | — | US | disclosed |