SCHEMBL16728007

CC(C)C(OCc1cn([C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c2nc(N)[nH]c(=O)c12)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	3/20	0.43

▸	P2RY4	P51582	3/20	0.43

▸	P2RY6	Q15077	3/20	0.43

▸	POLB	P06746	2/20	0.43

▸	TYMS	P04818	5/20	0.39

▸	DTYMK	P23919	2/20	0.38

▸	FUT5	Q11128	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16728024	1.00	P2RY2 (0.43)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL16728016	1.00	P2RY2 (0.43)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL10177893	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL10177878	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL14680012	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL14680009	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL14679982	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL10177925	0.94	TYMS (0.40)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL14951031	0.92	P2RY2 (0.43)	P2RY2P2RY4P2RY6POLBTYMS
SCHEMBL14951030	0.92	P2RY2 (0.43)	P2RY2P2RY4P2RY6POLBTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9200319-B2	Nucleotides and nucleosides and methods for their use in DNA sequencing	LASERGEN, INC. (US)	2015-12-01	—	—	US	disclosed
US-20150140559-A1	NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING	LASERGEN, INC. (US)	2015-05-21	—	—	US	disclosed