SCHEMBL16728014

SCHEMBL16728014

CC(C)[C@@H](OCc1cn([C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 3/20 0.42
P2RY4 P51582 2/20 0.42
P2RY6 Q15077 2/20 0.42
POLB P06746 1/20 0.42
POLG P54098 2/20 0.41
TRPM2 O94759 1/20 0.39
DTYMK P23919 2/20 0.38
TYMS P04818 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666267 1.00 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL16728023 1.00 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL16728032 1.00 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL1515070 0.93 P2RY2 (0.43) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL14665882 0.93 P2RY2 (0.43) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL15139308 0.92 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL15139313 0.92 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL22115991 0.92 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL16728021 0.92 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG
SCHEMBL14680030 0.92 P2RY2 (0.42) P2RY2P2RY4P2RY6POLBPOLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200319-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2015-12-01 US disclosed
US-20150140559-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2015-05-21 US disclosed