SCHEMBL16728017

SCHEMBL16728017

O=c1[nH]c(=O)n([C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)cc1COCc1ccccc1-c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMS P04818 10/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1665942 1.00 TYMS (0.64) TYMS
SCHEMBL15139310 1.00 TYMS (0.64) TYMS
SCHEMBL1665663 0.91 TYMS (0.60) TYMS
SCHEMBL15139316 0.91 TYMS (0.60) TYMS
SCHEMBL15139311 0.90 POLB (0.58) TYMS
SCHEMBL1666080 0.90 POLB (0.58) TYMS
SCHEMBL16728018 0.90 POLB (0.58) TYMS
SCHEMBL1665828 0.87 TYMS (0.54) TYMS
SCHEMBL1667921 0.87 TYMS (0.54) TYMS
SCHEMBL15483802 0.87 TYMS (0.54) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200319-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2015-12-01 US disclosed
US-20150140559-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2015-05-21 US disclosed