Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 9/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 5/20 | 0.46 |
| ▸ | CHRNG | P07510 | 5/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 5/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16728262 | 0.96 | CHRND (0.47) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL16728263 | 0.88 | NPY4R (0.47) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL16728258 | 0.88 | NPY4R (0.45) | CHRND | |
| SCHEMBL16728266 | 0.88 | NPY4R (0.47) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL16728376 | 0.87 | NPY4R (0.42) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL16728260 | 0.85 | NPY4R (0.58) | — | |
| SCHEMBL16728364 | 0.85 | NPY4R (0.58) | — | |
| SCHEMBL16728365 | 0.85 | NPY4R (0.58) | — | |
| SCHEMBL16728256 | 0.85 | NPY4R (0.58) | — | |
| SCHEMBL16728347 | 0.85 | NPY4R (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015071356-A1 | HPYY(1 -36) HAVING A BETA-HOMOARGININE SUBSTITUTION AT POSITION 35 | NOVO NORDISK A/S (DK) | 2015-05-21 | — | — | WO | disclosed |