Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630110 | 0.83 | CYP2D6 (0.56) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL5606071 | 0.83 | CYP2D6 (0.56) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL3582437 | 0.83 | CYP2D6 (0.56) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL3576405 | 0.83 | CYP2D6 (0.56) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL7363110 | 0.82 | UGT2B7 (0.53) | UGT2B7SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL5455403 | 0.82 | UGT2B7 (0.53) | UGT2B7SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL19650503 | 0.82 | UGT2B7 (0.53) | UGT2B7SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL5319511 | 0.82 | UGT2B7 (0.53) | UGT2B7SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL7832132 | 0.79 | NR1I2 (0.58) | UGT2B7SLC1A3SLC1A2SLC1A1SLC6A2 | |
| SCHEMBL839944 | 0.78 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040482-B2 | Octapeptide compounds and therapeutic use thereof | IPSEN PHARMA S.A.S. (FR) | 2015-05-26 | — | — | US | disclosed |