Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 16/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 15/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730692 | 0.84 | CSNK1E (0.42) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL18171151 | 0.80 | CSNK1E (0.61) | CSNK1ECSNK1DRIPK2BTK | |
| SCHEMBL18171256 | 0.78 | CSNK1E (0.71) | CSNK1ECSNK1DBTK | |
| SCHEMBL16728553 | 0.75 | CSNK1E (0.57) | CSNK1ECSNK1DBTK | |
| SCHEMBL16699673 | 0.74 | CSNK1E (0.51) | CSNK1ECSNK1D | |
| SCHEMBL16728598 | 0.74 | CSNK1E (0.78) | CSNK1ECSNK1DBTK | |
| SCHEMBL16699976 | 0.72 | CSNK1E (0.47) | CSNK1ECSNK1DRIPK2BTK | |
| SCHEMBL16699157 | 0.71 | CSNK1E (0.46) | CSNK1ECSNK1DBTK | |
| SCHEMBL16711398 | 0.71 | CSNK1E (0.47) | CSNK1ECSNK1DBTK | |
| SCHEMBL16711516 | 0.69 | CSNK1E (0.48) | CSNK1ECSNK1DRIPK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |