Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 15/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 12/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709111 | 0.90 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL16709114 | 0.81 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL16728881 | 0.81 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL16728764 | 0.81 | CSNK1E (0.51) | CSNK1ECSNK1DPARP1 | |
| SCHEMBL16709049 | 0.80 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL16728861 | 0.80 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16728678 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DRORC | |
| SCHEMBL16728682 | 0.78 | CSNK1E (0.43) | CSNK1ECSNK1DRORC | |
| SCHEMBL16699428 | 0.77 | CSNK1E (0.46) | CSNK1ECSNK1D | |
| SCHEMBL16711454 | 0.77 | CSNK1E (0.58) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |